Evaluation of Antioxidant, Antigylcation and Antiurelithaisis Activity of Melia azedarach L.

Authors

  • Sana Shabeer Department of Botany, University of Gujrat, Hafiz Hayat Campus, Gujrat-50700, Pakistan
  • Khizar Hayat Bhatti Department of Botany, University of Gujrat, Hafiz Hayat Campus, Gujrat-50700, Pakistan
  • Zahid Anwar Department of Biochemistry and Biotechnology, University of Gujrat, Hafiz Hayat Campus, Gujrat-50700, Pakistan
  • Iqra Iqbal Department of Botany, University of Gujrat, Hafiz Hayat Campus, Gujrat-50700, Pakistan
  • Muhammad Ajaib Department of Botany, Mirpur University of Science and Technology, Bhimber -10040, AJK-Pakistan
  • Muhammad Ishtiaq Department of Botany, Mirpur University of Science and Technology, Bhimber -10040, AJK-Pakistan

Keywords:

Antiglycation, Antioxidant, Antiurelithaisis, Bovine Serum

Abstract

Antioxidant antiglycation and antiurelithaisis activity of leaves and fruit extract of Melia azedarach L. were investigated. The
antioxidant activity of Melia leaf and fruit extracts was measured through a 2, 2-diphenyl-1-picrylhydrazyl scavenging assay. The
highest Antioxidant activity in leaves methanolic extract was 78.7±0.01 and in fruit extract was 90%±0.01. Antioxidant activities
varied depending upon the concentration of the sample. Antiurelithaisis activity was checked through in vitro struvite crystal
growth inhibition that revealed the moderate prevention of kidney stone diseases. The antiglycation activity of leaf and fruit
extract was measured through Bovine Serum Assay (BSA). Two weeks experiment was performed after 14 days both leaf and fruit
extracts showed the highest activity depending upon concentrations of samples.

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Published

2022-07-05

How to Cite

Sana Shabeer, Khizar Hayat Bhatti, Zahid Anwar, Iqra Iqbal, Muhammad Ajaib, & Muhammad Ishtiaq. (2022). Evaluation of Antioxidant, Antigylcation and Antiurelithaisis Activity of Melia azedarach L. GU Journal of Phytosciences, 2(3), 162–170. Retrieved from https://jphytosci.com/index.php/GUJP/article/view/10

Issue

Vol. 2 No. 3 (2022): GU Journal of Phytosciences [July 2022]

Section

Articles

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